Christina Applegate (50) made it public in August 2021 that she had multiple sclerosis (MS). The actress is now preparing for a special day. "A very important ceremony is coming up," she tweeted. "This will be my first appearance since the MS diagnosis. Canes are now my new normal," she continues, posting a picture of different models of the walker. Her fans would still find out which of these "beauties" Applegate ultimately chose, the 50-year-old explains at the end.

In August 2021, she also tweeted about her illness: "I was diagnosed with MS a few months ago. It's been a strange journey. But I've had so much support from people I know who also have the disease. It's been a tough road. But, as we all know, there's always a way forward. Unless some asshole blocks it."

MS is not her first shock diagnosis: in 2008, the now 50-year-old was diagnosed with breast cancer at a very early stage. At that time, Applegate decided on a bilateral prophylactic mastectomy. In 2017, she also had her ovaries and fallopian tubes removed as a precaution.

Applegate's breakthrough role was as Kelly Bundy on the hit sitcom Awfully Nice Family (1987-1997). Since 2019 she can be seen in the Netflix series "Dead To Me".