On the way to a bachelor party, two young men from Hepperlingen die in their car and fall into a river. Their bodies are recovered and undertaker Lisa Taubenbaum (Anna Fischer) is entrusted to them. The two had celebrated a bachelor party together with Mario (Jakob Geßner), the owner of the car. But where is Mario? There is no trace of him. Mario's wife Conny (Ricarda Seifried) doesn't know whether to hope or fear.
Kai (Sebastian Bezzel) has the firm intention of converting his newly acquired house into a cozy nest for himself, his wife Ina (Nadja Becker) and the offspring. So he grabs his buddies Pedro (Manuel Cortez) and Ulf (Heiko Pinkowski), stocks up on everything he needs at the hardware store - and gets started. However, Kai reckoned without the house: the somewhat older walls vehemently resist the renovation measures of the do-it-yourself trio.
After Markus (Sebastian Ströbel) has spent the night with Nina (Josephin Busch), a special transport awaits him and the mountain rescue team: a tree that the entrepreneur Ralf Pichler (Bernhard Schir) is giving to his wife Romina (Doris Schretzmayer) for their silver wedding anniversary , to obscure the view of a power pole in front of their house. When Markus wants to get a signature from the Pichlers after a successful order, he finds that the celebration has been cancelled. Because Ralf has found out in an unpleasant way that Romina is having an affair - with Charly (Julian Waldner), of all people, her son Till's (Justus Czaja) best friend.
In the year 2740, agents Valerian (Dane DeHaan), a swashbuckling womanizer, and self-confident Laureline (Cara Delevingne) are on a government mission to maintain order in the universe. On a special mission in the intergalactic city of Alpha, where thousands of species live peacefully together, the duo encounters subversive forces that endanger not only the multi-million metropolis, but the entire galaxy.
In the department of the forensic doctor Dr. Fred Abel (Tim Bergmann) land two cases that couldn't be more different. While Abel is ordered to Transnistria by a request for official assistance to help with the investigation of two decomposed corpses, the young Berlin waitress Jana (Svenja Jung) is in the clutches of the psychopathic doctor Dr. Lenski (Harald Schrott), who wants to make her submissive with drugs.
