A multi-national investigation that included the Basque laboratory CIC BioGune found that non-alcoholic fat liver can be divided into three types. These are all caused by other than alcohol abuse. This discovery opens the way to personalized therapies for a disease that affects more than 25% of the adult population.
Jose Maria Mato, a scientist who directs the laboratory, has been doing this work for many years. The support of nearly twenty research groups as well as top hospitals in the United States and Europe have made it possible. Scientists analyzed 1,154 patients' cholesterol and triglycerides (serum lipomas) and found at least three types of the disease. This discovery, which will be clinically valuable for many years, will allow the development of therapies that are tailored to each of these subtypes.